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Hospitalization because of an infection is not uncommon in patients with cancer, and the occurrence of CRBSI in the patients with cancer has become one of the most serious complications in critical care units \[[@B9]\]. Although some studies have shown that CRBSI occurrence is significantly associated with the duration of antibiotic treatment \[[@B10][@B11][@B12]\], there has been a paucity of information regarding the effect of antibiotics on CRBSI in patients with cancer.
This study showed that administration of vancomycin hydrochloride or cefazolin sodium in the catheter in our hospital is a significant risk factor for CRBSI, although the efficacy of the antibiotics may vary depending on the use of the drugs. Because CRBSI is a common complication in critically ill patients, physicians need to pay attention to patients who are administered an antibiotic in the central venous catheter for more than 2 weeks.
This research was supported by a grant (no. 04-2015-0587) from the SNUBH Research Fund.
**Authors' Disclosures of Potential Conflicts of Interest:** No potential conflicts of interest relevant to this article were reported.
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